You don’t need to replace everything to make your desk feel better. Start with the space you already have and the things you use every day. A good setup grows around your routine.
Start with what stays.
Take everything off your desk, then put back the things you reach for daily. Keep your keyboard and mouse where your hands naturally rest, and leave an open area for a notebook or whatever you are working on. Move occasional-use items to a drawer or shelf.
Give the small things a home.
A cable that falls behind your desk every day is a small problem worth solving. Route the cables you keep plugged in, place a tray for loose pieces, or use a mat to define your working area. Choose the smallest change that fixes the actual annoyance.
Upgrade one friction point.
Notice what interrupts your day. Too few ports? A cramped keyboard? Audio that makes calls difficult? Write down that one problem before browsing. If a new accessory doesn’t solve it, let it wait.
The best setup is the one that supports your routine. Start with one useful change.